Overview
High resolution imaging of molecules and cells will be critical for understanding complex systems such as the nervous system, whether it be for the localization of specific neuron types within a region of the central nervous system, the branching pattern of dendritic trees, or the localization of molecules at the subcellular levels. In collaboration with researchers in biology, we are developing new image analysis methods for quantifying complex biological phenomena.
Related Publications
“Fully Automated Volumetric Classification in CT Scans for Diagnosis and Analysis of Normal Pressure Hydrocephalus”, Angela Zhang, Po-Yu Kao, Ashutosh Shelat, Ronald Sahyouni, Jefferson Chen, B.S. Manjunath, arXiv, 1901.09088, Jan. 2019.
“Brain Tumor Segmentation and Tractographic Feature Extraction from Structural MR Images for Overall Survival Prediction”, Po-Yu Kao, Thuyen Ngo, Angela Zhang, Jefferson W. Chen, B.S. Manjunath, 4th International Workshop, BrainLes 2018, Held in Conjunction with MICCAI 2018, Nov. 2018.
“Unsupervised 3-D Feature Learning for Mild Traumatic Brain Injury”, Po-Yu Kao, Eduardo Rojas, Jefferson W. Chen, Angela Zhang, B. S. Manjunath, International Workshop on Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries, pp. 282-290, Athens, Greece, Oct. 2016.
“Biological imaging software tools”, K. Eliceiri, M. R. Berthold, I. G. Goldberg, L. Ibanez, B. S. Manjunath, M. E. Martone, R. F. Murphy, H. Peng, A. L. Plant, B. Roysam. N. Stuurmann, J. R. Swedlow, P. Tomancak and A. E. Carpenter, Nature Methods, vol. 9, pp. 6977-710, Nature Publishing Group, Jun. 2012.
“Structure-Forming Corals and Sponges and Their Use as Fish Habitat in Bering Sea Submarine Canyons”, Robert J. Miller, John Hocevar, Robert P. Stone, Dmitry V. Fedorov, PLoS ONE, vol. 7, no. 3, 2012.
“Silencing of CDK5 Reduces Neurofibrillary Tangles in Transgenic Alzheimer's Mice”, Diego Piedrahita, Israel Hernandez, Alejandro Lopez-Tobon, Dmitry Fedorov, Boguslaw Obara, B. S. Manjunath, Ryan L. Boudreau, Beverly Davidson, Frank LaFerla, Juan Carlos Gallego-Gomez, Kenneth S. Kosik, and Gloria Patricia Cardona-Gomez, Journal of Neuroscience, vol. 30, no. 42, pp. 13966-13976, Oct. 2010.
“Bisque: A Platform for Bioimage Analysis and Management”, Kristian Kvilekval, Dmitry Fedorov, Boguslaw Obara, Ambuj Singh and B.S. Manjunath, Bioinformatics, vol. 26, no. 4, pp. 544-552, Feb. 2010.
